Molecularformula:C29H48O2
Cas No.:604-35-3
Molecularweight:428.7
Appearance: White powder
Melting point: 112-115 ℃ Loss on
Drying: Less than 1%
Assay: ≥97.0 %
Cholesteryl acetate was a flowing liquid exhibiting optical properties previously attributed only to crystals. The discovery brought into question the belief of the time that only three states of matter could exist (liquid, solid, and gas). More recently, liquid crystals such as cholesteryl acetate have come to be used in cosmetics, wrist watches, thermometers, propane tank volume indicators, video displays, and in the "mood rings" of the late 1970s fad.
Synthesis of cholesteryl acetate from cholesterol involves heating the cholesterol in a solution of acetic acid and acetic anhydride. Although synthesized in the laboratory and on a commercial scale, cholesteryl acetate exists as a naturally occurring substance as well. For example, it is found as one of the three cholesterol esters composing the outer cuticle layer lipid coating of the brown dog tick
Cholesteryl acetate disrupts the packing order of the DMPC acyl chains from 0 to ca. 35 mol% cholesterylacetate. As the concentration of cholesterylacetate is increased from ca. 14 to ca. 35 mol% the DMPC acyl chains become more ordered and cholesterylacetate appears to form a crystalline phase that remains inn suspension with the lecithin. As more cholesterylacetate is added, these crystalline regions become larger and begin to form a precipitate which is structurally identical to those particles which remain in suspension.
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