What is enalapril?

Enalapril for white or white crystalline powder, odourless, tasteless. Easily dissolved in methanol, slightly soluble in water, slightly soluble in acetone. The melting point of 142-142 ℃ (decomposition). For angiotensin converting enzyme inhibitor, absorbed in the liver to ester hydrolysis is enalaprilat, and play the role of inhibition of angiotensin converting enzyme. Suitable for all kinds of degree of hypertension, renovascular hypertension, and diabetes treatment for hypertension patients; Can also be used for the treatment of chronic congestive heart failure, especially in the conventional application of digitalis or diuretic is difficult to control, can delay the progress of clinical symptoms of congestive heart failure and minimize the need for hospitalization. This product effect is better than that of the captopril, adverse reactions and lighter, so it is increasingly widely used, in the treatment of high blood pressure drug of choice. With other anti-hypertensive drugs, especially the diuretic step-down, enhanced by use of this product should be discontinued before the diuretic or start from small doses. This product can make the potassium rises, unfavorable and potassium diuretic or potassium supplement share.

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Pharmacology of Urokinase (UK)

Urokinase is by fresh urine separation, refining and a protein enzyme, usually white or white freeze-dried block or powder. Mainly made of enzymes to dissolve thrombus. It can activate fibrinolytic enzymes in the body into a fibrinolytic enzyme, thereby hydrolysis fibrin make new form of thrombolysis. It should be used immediately after dissolved and should not be stored.

pharmacological

1, the direct effects on endogenous fibrinolysis system, which can catalytic cracking fibrinolytic enzyme into a fibrinolytic enzyme.

Endogenous fibrinolysis system not only can degradation of fibrin clot, also can degrade fibrinogen in blood, and clotting factor Ⅴ and blood coagulation factor Ⅷ etc, which play a role of thrombolysis, the newly formed blood clots quick effect, the effect is good.

2 ADP enzyme activity, improve the blood vessels, inhibit the platelet aggregation induced by ADP, prevent thrombosis.

After intravenous drip, the patient's body fibrinolytic enzyme activity increased significantly; Stopped a few hours later, fibrinolytic enzyme activity to restore the original level, but the level of plasma fibrin and fibrinogen is reduced, and their degradation products increase sustainable 12-24 hours.

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The chemical composition of Ephedra

Ephedra the divergence of cold medicine in Chinese medicine or Chinese medicine; Ancient alias Long Sha, British Columbia. Consists of three plants of the genus Ephedra, Ephedra sinica (Ephedra sinica), horsetail Ephedra (Ephedra equisetina) with the Ephedra (Ephedra intermedia), used parts for CaoZhiJing.

Chemical composition: including alkaloids was 1% ~ 2%, 40% ~ 90% ephedrine, pseudoephedrine followed by, go ephedrine, pseudoephedrine, methyl ephedrine and pseudoephedrine, and traces of alpha - N methyl ephedrine, pseudoephedrine, d - a N methyl l go a methyl ephedrine, d a methyl pseudoephedrine, ephedra times alkali.

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Vincristine can antitumor

Vincristine is apocynaceae plant vinca alkaloids extracted, because of anti-tumor effect is good, at present the preparations as clinical antitumor drugs. Keyword extraction and separation of structure and properties of pharmacological effects therapeutic method pharmacokinetic

Vincristine cancer and curative effect of about 10 times higher than that of vinblastine, can be used in the treatment of acute lymphocytic leukemia, curative effect is better, for other acute leukemia, Hodgkin's disease, lymphatic sarcoma, the reticular cell sarcoma and breast cancer also has curative effect. With VLB (vinblastine), los los together new and generic los wash dean in vinca alkaloids in flowers (Vincamajor). With the cell division (mitosis) stop in the medium term, this is similar to colchicine, but its effect was stronger than colchicine. Like colchicine can combine with tubulin and inhibit its biological activity, but the combination of different parts. It is different from colchicine outside of tubulin proteins such as actin and 10 nanometers filament protein also play a role. In clinical medicine, as one of the anticancer agent and has been applied, especially in hematopoietic organ lesions is effective. Vinblastine sulfate can be used in the treatment of Hodgkin's disease and chorionic carcinoma, curative effect is better; For lymphatic sarcoma, the reticular cell sarcoma, acute leukemia (VP, VDLP scheme of "V" for vincristine, D for soft erythromycin, "L" for winter amidase door, "P" for prednisone), breast cancer, renal tumor, ovarian and testicular cancer, neuroblastoma, and malignant melanoma also have certain curative effect.

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The introduction of the Cetirizine Di Hcl

English name: Cetirizine

English synonyms: (2 - (4 - ((4 chlorophenyl) phenylmethyl) - 1 piperazinyl) ethoxy) - aceticaci; (2 - (4 - ((4 chlorophenyl) phenylmethyl] 1 piperazinyl) ethoxy) aceticacid; CETIRIZINE. (2 - (4 - [(4 - CHLORO - PHENYL) - PHENYL - METHYL] - PIPERAZIN - 1 - YL) - ETHOXY) - ACETIC ACID; Cetirizine Hydrochloride BP; Cetirizine (Cetrizine) Di HCl;Cetirizine Di Hcl; CERTIRIZINE 2 HCL; CETIRIZINE IMPURITY A (RS) - 1 - [(4 CHLOROPHENYL) PHENYLMETHYL] PIPERAZINE EPC STANDARD (CRM)

CAS no. : 51-83881-0

Molecular formula: C21H25ClN2O3

Molecular weight: 388.89

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How to identify Riboflavin-5-phosphate sodium

Identification test: Riboflavin - 5 - phosphate sodium solubility soluble in water. Insoluble in ethanol. According to the OT - 42 method determination.

Than the sample rotation under 100 ℃ in the phosphorus pentoxide in vacuum drying after 5 h, with a 20% (W/V) hydrochloric acid as solvent, the preparation of 1.5% (W/V) sample liquid, then according to the conventional method. The [alpha] D20 shall be the + 38 ° ~ 42 °. Sodium salt in IT - 28 method determination of the sodium sulphate ash content.

Sample solution at 375 nm and 267 nm wavelength of maximum absorbance ratio is 0.30 ~ 0.34, at 444 nm and 26.7 nm ratio is 0.35 ~ 0.40.

Content analysis: content analysis shall be carried out under the direct light. Take a sample of 100 mg in a 500 ml volumetric flask brown, add water, 100 ml and 2.5 ml glacial acetic acid, water constant volume. Take the 20.0 ml liquid into a 200 ml volumetric flask, brown and 1.4% (W/V) sodium acetate solution 3.5 ml, constant volume with water. The determination of maximum absorbance of the solution at 444 nm (A).

The total amount of pigment (A x = 5000/328 (W) x 1.367

Type of W - sample quantity, g.

Purpose: vitamin drugs, used in the treatment of a variety of VB2 deficiency, but also can be used as a food additive

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From:Natural herbal extracts

What is lafutidine?

Lafutidine (INN) is a additional bearing H2 receptor adversary accepting multimodal apparatus of action. It is currently marketed in Japan (Stogar) China (Lemeiting) and India (Lafaxid) It not alone suppresses belly acerbic secretion, but aswell has cytoprotective backdrop by the advantage of its acreage to abet the collagen amalgam in the belly mucosa.It has a atypical apparatus of activity in accession to blocking the H2 receptors , it decreases deepening by modulating Capsaicin- acute gene-related peptide (CGRP) and vanilloid receptors It is aswell begin to activate mucin biosynthesis and advance the amends of damaged mucosa.

Acid Suppressive action:Lafutidine is captivated in the baby intestine, alcove belly beef via the systemic circulation, and again anon and rapidly binds to belly corpuscle histamine H2 receptors, thereby inhibiting the dispatch of cAMP and a resultant abatement in acerbic assembly (antisecretory action).It causes a abiding access in intracellular Ca2+ ion absorption in endothelial beef consistent in the absolution of Calcitonin Gene Related Peptide (CGRP), which causes acerbic abolishment by abbreviating the vagal tone.Lafutidine aswell increases claret somatostatin levels which decreases beard of gastrin from G cells. This abatement in gastrin causes inhibition of parietal cells, consistent in abatement in belly acerbic secretion.

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The purpose of tiopronin

Tiopronin is acclimated primarily for cystinuria and is able-bodied accepted in the cystinuric community. Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in aboriginal childhood.

It may aswell be acclimated for Wilson's ache (an afflict of chestnut in the body), and assertive types of attenuate arthritis, admitting tiopronin is not an anti-inflammatory.

Tiopronin is aswell sometimes acclimated as a stabilizing abettor for metal nanoparticles. The thiol accumulation binds to the nanoparticles, preventing coagulation.

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From:Natural herbal extracts

What is norfloxacin?

Norfloxacin is a constructed chemotherapeutic antibacterial abettor occasionally acclimated to amusement accepted as able-bodied as complicated urinary amplitude infections.It is awash beneath assorted cast names with the a lot of accepted getting Noroxin. In anatomy of ophthalmic solutions it is accepted as Chibroxin (Apiflox eye drops in Jordan ). Norfloxacin is a aboriginal bearing constructed fluoroquinolone (quinolone) developed by Kyorin Seiyaku K.K. (Kyorin).
The accountant uses for norfloxacin are absolutely bound as norfloxacin is to be advised a biologic of endure resort if all added antibiotics accept failed. There are currently alone three accustomed uses in the developed citizenry (one of which is belted and the added abortive due to bacterial resistance. Chibroxin[8] (ophthalmic) is accustomed for use in accouchement earlier than one year of age.
Norfloxacin interacts with a amount of added drugs, as able-bodied as a amount of herbal and accustomed supplements. Such interactions access the accident of anticoagulation and the accumulation of non-absorbable complexes, as able-bodied as accretion the accident of toxicity.

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What is Sodium Hyaluronate (Hyaluronic Acid)?

Hyaluronan (also alleged Hyaluronic Acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan broadcast broadly throughout connective, epithelial, and neural tissues. It is different a part of glycosaminoglycans in that it is nonsulfated, forms in the claret film instead of the Golgi, and can be actual large, with its atomic weight generally extensive the millions.One of the arch apparatus of the extracellular matrix, hyaluronan contributes decidedly to corpuscle admeasurement and migration, and may aswell be complex in the progression of some cancerous tumors.
The boilerplate 70 kg (154 lbs) being has almost 15 grams of hyaluronan in the body, one-third of which is angry over (degraded and synthesized) every day.Hyaluronic acerbic is aswell a basic of the accumulation A streptococcal extracellular capsule,and is believed to play a role in virulence.


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The basic information of the Hyocholic acid

CAS: 547-75-1
Name: HYOCHOLIC ACID
English Synonyms: HYOCHOLIC ACID; GAMMA MURICHOLIC; LAMBDA-MURICHOLIC ACID; 5B-CHOLAN-24-OIC ACID-3A, 6A, 7A-TRIOL; 3α, 6α, 7α-Trihydroxy-5β-cholan-24-oic acid; 3A, 6A-7A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID; 5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA, 7-ALPHA-TRIOL; 5-BETA-CHOLAN-24-OIC ACID-3-ALPHA ,6-ALPHA ,7-ALPHA-TRIOL; 3-ALPHA ,6-ALPHA ,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID; 3,6,7-trihydroxy-, (3alpha, 5beta, 6alpha, 7alpha)-cholan-24-oicaci
Chinese name: Pig acid
Chinese Synonyms: pig bile
CBNumber: CB3141135
MF: C24H40O5
Molecular Weight: 408.57


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