Tuesday, March 20, 2012

Uses of Cholesteryl pelargonate (Cholesterol pelargonate)?

Cholesteryl nonanoate, also called cholesteryl pelargonate, 3β-cholest-5-en-3-ol nonaoate or cholest-5-ene-3-β-yl nonanoate, is an ester of cholesterol and nonanoic acid. It is a liquid crystal material forming cholesteric liquid crystals with helical structure. It forms spherulite crystals.
Uses
It is used in some hair colors, make-ups, and some other cosmetic preparations. It is also used in some pleochroic dyes and together with e.g. cholesteryl oleyl carbonate and cholesteryl benzoate in some thermochromic applications.
Cholesteryl pelargonate (Cholesterol pelargonate) can be also used as a component of the liquid crystals used for liquid crystal displays.
Cholesterol is a steroid alcohol that is essentially insoluble in aqueous solutions. Cholesterol can be esterified with a fatty acid to form cholesteryl esters. The latter form discrete lipid droplets in cells, especially in cells of steroidogenic tissues, and in the lipid core of low-density lipoproteins in the blood. Cholesterol is a fatty lipid sparingly insoluble in water but soluble in a number of organic solvents. It is the most common sterol of eukaryotes which a key constituent of cell membranes and works as the precursor of bile acids, cholecalciferol (vitamin D)  and steroid hormones including cortisol, cortisone,  aldosterone and sex hormone progesterone in vertebrates. Cholesterol is used as an emulsifying agent in pharmaceuticals. The most cholesterols are synthesized by the liver and other tissues include the adrenal glands and reproductive organs. Some cholesterol  is absorbed from dietary sources. The largest concentration of cholesterol is in the myelin sheath that surrounds nerves and in the plasma membrane that surrounds all cells in vertebrates (25% of brain lipid is cholesterol).
Cholesterol can be esterified with a fatty acid to form cholesteryl esters which form discrete lipid droplets in cells, especially in cells of steroidogenic tissues, and in the lipid core of low-density lipoproteins in the blood. The collection on the walls of arteries interferes with the flow of blood. The High level of cholesterol in the blood is a major risk factor for coronary heart diseases. Cholesteric materials are liquid crystals of mesomorphic phase in which molecules are parallel to each other within the plane of a layer, but the direction is oriented in loose parallel lines to form a helix through the layers. Cholesteric materials are temperature sensitive and have color changing ability upon temperature
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