Sunday, December 29, 2013

What is enalapril?


Enalapril for white or white crystalline powder, odourless, tasteless. Easily dissolved in methanol, slightly soluble in water, slightly soluble in acetone. The melting point of 142-142 ℃ (decomposition). For angiotensin converting enzyme inhibitor, absorbed in the liver to ester hydrolysis is enalaprilat, and play the role of inhibition of angiotensin converting enzyme. Suitable for all kinds of degree of hypertension, renovascular hypertension, and diabetes treatment for hypertension patients; Can also be used for the treatment of chronic congestive heart failure, especially in the conventional application of digitalis or diuretic is difficult to control, can delay the progress of clinical symptoms of congestive heart failure and minimize the need for hospitalization. This product effect is better than that of the captopril, adverse reactions and lighter, so it is increasingly widely used, in the treatment of high blood pressure drug of choice. With other anti-hypertensive drugs, especially the diuretic step-down, enhanced by use of this product should be discontinued before the diuretic or start from small doses. This product can make the potassium rises, unfavorable and potassium diuretic or potassium supplement share.
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Friday, December 27, 2013

Pharmacology of Urokinase (UK)



Urokinase is by fresh urine separation, refining and a protein enzyme, usually white or white freeze-dried block or powder. Mainly made of enzymes to dissolve thrombus. It can activate fibrinolytic enzymes in the body into a fibrinolytic enzyme, thereby hydrolysis fibrin make new form of thrombolysis. It should be used immediately after dissolved and should not be stored.
pharmacological
1, the direct effects on endogenous fibrinolysis system, which can catalytic cracking fibrinolytic enzyme into a fibrinolytic enzyme.
Endogenous fibrinolysis system not only can degradation of fibrin clot, also can degrade fibrinogen in blood, and clotting factor Ⅴ and blood coagulation factor Ⅷ etc, which play a role of thrombolysis, the newly formed blood clots quick effect, the effect is good.
2 ADP enzyme activity, improve the blood vessels, inhibit the platelet aggregation induced by ADP, prevent thrombosis.
After intravenous drip, the patient's body fibrinolytic enzyme activity increased significantly; Stopped a few hours later, fibrinolytic enzyme activity to restore the original level, but the level of plasma fibrin and fibrinogen is reduced, and their degradation products increase sustainable 12-24 hours.

Thursday, December 26, 2013

The chemical composition of Ephedra


Ephedra the divergence of cold medicine in Chinese medicine or Chinese medicine; Ancient alias Long Sha, British Columbia. Consists of three plants of the genus Ephedra, Ephedra sinica (Ephedra sinica), horsetail Ephedra (Ephedra equisetina) with the Ephedra (Ephedra intermedia), used parts for CaoZhiJing.
Chemical composition: including alkaloids was 1% ~ 2%, 40% ~ 90% ephedrine, pseudoephedrine followed by, go ephedrine, pseudoephedrine, methyl ephedrine and pseudoephedrine, and traces of alpha - N methyl ephedrine, pseudoephedrine, d - a N methyl l go a methyl ephedrine, d a methyl pseudoephedrine, ephedra times alkali.




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Monday, December 23, 2013

Vincristine can antitumor



Vincristine is apocynaceae plant vinca alkaloids extracted, because of anti-tumor effect is good, at present the preparations as clinical antitumor drugs. Keyword extraction and separation of structure and properties of pharmacological effects therapeutic method pharmacokinetic
Vincristine cancer and curative effect of about 10 times higher than that of vinblastine, can be used in the treatment of acute lymphocytic leukemia, curative effect is better, for other acute leukemia, Hodgkin's disease, lymphatic sarcoma, the reticular cell sarcoma and breast cancer also has curative effect. With VLB (vinblastine), los los together new and generic los wash dean in vinca alkaloids in flowers (Vincamajor). With the cell division (mitosis) stop in the medium term, this is similar to colchicine, but its effect was stronger than colchicine. Like colchicine can combine with tubulin and inhibit its biological activity, but the combination of different parts. It is different from colchicine outside of tubulin proteins such as actin and 10 nanometers filament protein also play a role. In clinical medicine, as one of the anticancer agent and has been applied, especially in hematopoietic organ lesions is effective. Vinblastine sulfate can be used in the treatment of Hodgkin's disease and chorionic carcinoma, curative effect is better; For lymphatic sarcoma, the reticular cell sarcoma, acute leukemia (VP, VDLP scheme of "V" for vincristine, D for soft erythromycin, "L" for winter amidase door, "P" for prednisone), breast cancer, renal tumor, ovarian and testicular cancer, neuroblastoma, and malignant melanoma also have certain curative effect.


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From:Natural herbal extracts

Thursday, December 19, 2013

The introduction of the Cetirizine Di Hcl



English name: Cetirizine
English synonyms: (2 - (4 - ((4 chlorophenyl) phenylmethyl) - 1 piperazinyl) ethoxy) - aceticaci; (2 - (4 - ((4 chlorophenyl) phenylmethyl] 1 piperazinyl) ethoxy) aceticacid; CETIRIZINE. (2 - (4 - [(4 - CHLORO - PHENYL) - PHENYL - METHYL] - PIPERAZIN - 1 - YL) - ETHOXY) - ACETIC ACID; Cetirizine Hydrochloride BP; Cetirizine (Cetrizine) Di HCl;Cetirizine Di Hcl; CERTIRIZINE 2 HCL; CETIRIZINE IMPURITY A (RS) - 1 - [(4 CHLOROPHENYL) PHENYLMETHYL] PIPERAZINE EPC STANDARD (CRM)
CAS no. : 51-83881-0
Molecular formula: C21H25ClN2O3
Molecular weight: 388.89

Monday, December 16, 2013

How to identify Riboflavin-5-phosphate sodium


Identification test: Riboflavin - 5 - phosphate sodium solubility soluble in water. Insoluble in ethanol. According to the OT - 42 method determination.
Than the sample rotation under 100 ℃ in the phosphorus pentoxide in vacuum drying after 5 h, with a 20% (W/V) hydrochloric acid as solvent, the preparation of 1.5% (W/V) sample liquid, then according to the conventional method. The [alpha] D20 shall be the + 38 ° ~ 42 °. Sodium salt in IT - 28 method determination of the sodium sulphate ash content.
Sample solution at 375 nm and 267 nm wavelength of maximum absorbance ratio is 0.30 ~ 0.34, at 444 nm and 26.7 nm ratio is 0.35 ~ 0.40.
Content analysis: content analysis shall be carried out under the direct light. Take a sample of 100 mg in a 500 ml volumetric flask brown, add water, 100 ml and 2.5 ml glacial acetic acid, water constant volume. Take the 20.0 ml liquid into a 200 ml volumetric flask, brown and 1.4% (W/V) sodium acetate solution 3.5 ml, constant volume with water. The determination of maximum absorbance of the solution at 444 nm (A).
The total amount of pigment (A x = 5000/328 (W) x 1.367
Type of W - sample quantity, g.
Purpose: vitamin drugs, used in the treatment of a variety of VB2 deficiency, but also can be used as a food additive

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From:Natural herbal extracts

Thursday, December 12, 2013

What is lafutidine?



Lafutidine (INN) is a additional bearing H2 receptor adversary accepting multimodal apparatus of action. It is currently marketed in Japan (Stogar) China (Lemeiting) and India (Lafaxid) It not alone suppresses belly acerbic secretion, but aswell has cytoprotective backdrop by the advantage of its acreage to abet the collagen amalgam in the belly mucosa.It has a atypical apparatus of activity in accession to blocking the H2 receptors , it decreases deepening by modulating Capsaicin- acute gene-related peptide (CGRP) and vanilloid receptors It is aswell begin to activate mucin biosynthesis and advance the amends of damaged mucosa.
Acid Suppressive action:Lafutidine is captivated in the baby intestine, alcove belly beef via the systemic circulation, and again anon and rapidly binds to belly corpuscle histamine H2 receptors, thereby inhibiting the dispatch of cAMP and a resultant abatement in acerbic assembly (antisecretory action).It causes a abiding access in intracellular Ca2+ ion absorption in endothelial beef consistent in the absolution of Calcitonin Gene Related Peptide (CGRP), which causes acerbic abolishment by abbreviating the vagal tone.Lafutidine aswell increases claret somatostatin levels which decreases beard of gastrin from G cells. This abatement in gastrin causes inhibition of parietal cells, consistent in abatement in belly acerbic secretion.


Wednesday, December 11, 2013

The purpose of tiopronin



Tiopronin is acclimated primarily for cystinuria and is able-bodied accepted in the cystinuric community. Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in aboriginal childhood.
It may aswell be acclimated for Wilson's ache (an afflict of chestnut in the body), and assertive types of attenuate arthritis, admitting tiopronin is not an anti-inflammatory.
Tiopronin is aswell sometimes acclimated as a stabilizing abettor for metal nanoparticles. The thiol accumulation binds to the nanoparticles, preventing coagulation.

Monday, December 9, 2013

What is norfloxacin?



Norfloxacin is a constructed chemotherapeutic antibacterial abettor occasionally acclimated to amusement accepted as able-bodied as complicated urinary amplitude infections.It is awash beneath assorted cast names with the a lot of accepted getting Noroxin. In anatomy of ophthalmic solutions it is accepted as Chibroxin (Apiflox eye drops in Jordan ). Norfloxacin is a aboriginal bearing constructed fluoroquinolone (quinolone) developed by Kyorin Seiyaku K.K. (Kyorin).
The accountant uses for norfloxacin are absolutely bound as norfloxacin is to be advised a biologic of endure resort if all added antibiotics accept failed. There are currently alone three accustomed uses in the developed citizenry (one of which is belted and the added abortive due to bacterial resistance. Chibroxin[8] (ophthalmic) is accustomed for use in accouchement earlier than one year of age.
Norfloxacin interacts with a amount of added drugs, as able-bodied as a amount of herbal and accustomed supplements. Such interactions access the accident of anticoagulation and the accumulation of non-absorbable complexes, as able-bodied as accretion the accident of toxicity.


Thursday, December 5, 2013

What is Sodium Hyaluronate (Hyaluronic Acid)?



Hyaluronan (also alleged Hyaluronic Acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan broadcast broadly throughout connective, epithelial, and neural tissues. It is different a part of glycosaminoglycans in that it is nonsulfated, forms in the claret film instead of the Golgi, and can be actual large, with its atomic weight generally extensive the millions.One of the arch apparatus of the extracellular matrix, hyaluronan contributes decidedly to corpuscle admeasurement and migration, and may aswell be complex in the progression of some cancerous tumors.
The boilerplate 70 kg (154 lbs) being has almost 15 grams of hyaluronan in the body, one-third of which is angry over (degraded and synthesized) every day.Hyaluronic acerbic is aswell a basic of the accumulation A streptococcal extracellular capsule,and is believed to play a role in virulence.


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From:Natural herbal extracts

Tuesday, December 3, 2013

The basic information of the Hyocholic acid





CAS: 547-75-1
Name: HYOCHOLIC ACID
English Synonyms: HYOCHOLIC ACID; GAMMA MURICHOLIC; LAMBDA-MURICHOLIC ACID; 5B-CHOLAN-24-OIC ACID-3A, 6A, 7A-TRIOL; 3α, 6α, 7α-Trihydroxy-5β-cholan-24-oic acid; 3A, 6A-7A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID; 5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA, 7-ALPHA-TRIOL; 5-BETA-CHOLAN-24-OIC ACID-3-ALPHA ,6-ALPHA ,7-ALPHA-TRIOL; 3-ALPHA ,6-ALPHA ,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID; 3,6,7-trihydroxy-, (3alpha, 5beta, 6alpha, 7alpha)-cholan-24-oicaci
Chinese name: Pig acid
Chinese Synonyms: pig bile
CBNumber: CB3141135
MF: C24H40O5
Molecular Weight: 408.57


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From:Chemical Reagent

Thursday, November 21, 2013

Information about Anti-Dengue Antibody




Dengue is an infectious disease caused by the Dengue virus, it is belong to Aedes (also called Edith mosquito, Aedes) of white spot mosquito (Aedes albopictus) with Egypt spot mosquito, Aedes aegypti) after the first bite patients, become "vector mosquitoes," other healthy people could be infected by this vector mosquitoes. Likely excessive fatigue and depression symptoms, accidentally the sick will deteriorate to dengue to spill blood heat, and further bleeding, shock, and even death. Dengue fever of complications is often the patient to death. In general dengue fever are mainly distributed in tropical and subtropical regions.

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From:Natural herbal extracts

Wednesday, November 20, 2013

The basic information of the 4,5-Difluoro-2-Nitroaniline



Chinese name: 4,5 - difluoro-2 - nitroaniline
Chinese Synonyms: 4,5 - difluoro-2 - nitroaniline China; - nitro-4 ,5 - Difluoroaniline
English name: 4,5-DIFLUORO-2-NITROANILINE
English Synonyms: 4,5-DIFLUORO-2-NITROANILINE; 3,4-DIFLUORO-2-NITROANILINE; 3,4-DIFLUORO-6-NITRO ANILINE; BUTTPARK 19 \ 04-57; 4,5-DIFLUORO-2-NITROANILINE 99%; 4,5-Difluoro-2-nitroaniline, 98%; 4,5-DIFLUORO-2-NITRO; 2-Amino-4 ,5-difluoronitrobenzene
CAS: 78056-39-0
Formula: C6H4F2N2O2
MW: 174.1
EINECS Number:
Related Categories: Aniline; Miscellaneous; Anilines, Amides & Amines; Fluorine Compounds; Nitro Compounds; Amines; C2 to C6; Nitrogen Compounds; aromatics; Aryl Fluorinated Building Blocks; Building Blocks; C6; Chemical Synthesis; Fluorinated Building Blocks; Nitrogen Compounds; Organic Building Blocks; Organic Fluorinated Building Blocks; Other Fluorinated Organic Building Blocks; amines; benzene series; fluorine; nitro; NULL
Mol File: 78056-39-0.mol


Sunday, November 17, 2013

The main purpose of the Sodium fluoride



Sodium fluoride: shine colorless crystals or white powder, specific gravity 2.25, melting point 993 ℃ the boiling point of 1695 ℃. Soluble in water (20 ° C solubility 10 ° C 3.66, 4.06, 4.22, 40 °, 30 ° C C 4.4, 60 ° C 4.68, 4.89, 100 °, 80 ° C C5.08), hydrofluoric acid, slightly dissolve into alcohol. Weakly alkaline aqueous solution, but soluble in hydrofluoric acid and hydrogen fluoride sodium, can corrode the glass. Poisonous!
Main application: in coating industry for phosphating accelerator, stability of the phosphating liquid and phosphating refinement, improvement of phosphating film performance. Aluminum and its alloy phosphating damaging, closed a large negative catalysis of Al3 +, phosphating smoothly wood preservative, agricultural pesticides, fungicides, medicine, preservatives, welding flux, alkaline zincate galvanized additive and enamel, paper industry, etc.


Thursday, November 7, 2013

Isoflurane anesthesia is a good medicine





Isoflurane can rapid induction of anesthesia, the patient recovered from anesthesia is faster. Isoflurane had mild irritation, which limits its induction rate, but the throat and the trachea bronchial secretion is not much. Throat reflection can alleviate quickly. Isoflurane anesthesia level changes quickly. The drug is a kind of deep breathing inhibitors, therefore must pay close attention to breathing and provide respiratory support when necessary. Anesthesia increase, reduce tidal volume but breathing rate unchanged. Respiratory depression can part by surgical stimulation inside. Sigh isoflurane can stimulate sexual response, similar to that of desflurane anesthesia in the ether and grace to see, but the frequency is far lower than the desflurane.
Anesthesia to blood pressure lowering but operations to stimulate the deflection to the normal direction. Anesthesia level increases with the corresponding drop in blood pressure. N2O reduction in inhaling isoflurane concentration, so the blood pressure lowering effect is weak in the use of isoflurane. Rhythm of the heart no abnormal change. Under the condition of the control of ventilation and PaCO2, cardiac output by increasing heart rate compensation per the decrease of cardiac output and maintain stability. Naturally occurring in the process of ventilation hypercarbia blood disease further stimulate the heart rate increases, the cardiac output is higher than the level of the waking state. Isoflurane can't make the experimental dog myocardial adrenaline increased sensitivity of exogenous. Limited experimental data show that subcutaneous injection of 0.25 mg epinephrine for isoflurane anesthesia patients of ventricular arrhythmias without aggravating tendency.


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From:pharmaceutical chemicals

Tuesday, November 5, 2013

Oxymetholone adapted to the symptoms




Oxymetholone clinically used for chronic wasting disease, infirm, weak after illness and angular, infantile hypoplasia, osteoporosis, aplastic anemia, white blood cells reduce disease, hyperlipidemia, etc. Can have nausea, edema, liver dysfunction, jaundice. Young women with menstrual delay phenomenon, withdrawal can be restored. Medicine for children less than 30 days, the adult does not exceed 90 days. Withdrawal after the break can be used again. Hydroxy methylene dragon is also a medium banned athletes use stimulant drug. Promote the formation and development of male sex organs, mature, and against the estrogen, inhibit the growth of endometrial and ovarian pituitary function. Promote the synthesis of protein metabolism, excited bone marrow hematopoietic function, stimulate the production of blood cells. Clinical used for male hypogonadism disease, disease of testosterone and cryptorchidism); Gynecological diseases, such as menorrhagia, uterine fibroids, endometriosis, senile osteoporosis and pediatric aplastic anemia.

Sunday, November 3, 2013

The principle of Palladium carbon catalyst





Palladium - chemical symbol Pd, it is silvery white metal, soft, good ductility and plasticity, forging, rolling and drawing. Block metal palladium can absorb a large amount of hydrogen gas, make significant swelling volume, brittle or even broken into pieces
Carbon palladium catalyst is formed in the metal palladium load to activated carbon type load hydrofining catalyst, used to deal with the refining terephthalic acid raw material, the production of purified terephthalic acid. Carbon palladium catalyst has the different process of PTA filling quantity, such as Beijing, Shanghai yanshan petrochemical, liaoyang petrochemical, luoyang petrochemical and tianjin petrochemical refining enterprises, the successful industrial application. 


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From:Chemical Catalysts

Friday, November 1, 2013

What is Nandrolone ?




Nandrolone (19-nortestosterone) is an anabolic steroid. Nandrolone is a lot of frequently awash commercially as its decanoate ester (Deca-Durabolin) and beneath frequently as a phenylpropionate ester (Durabolin). Nandrolone decanoate is acclimated in the analysis of osteoporosis in postmenopausal women (though now not recommended) at a dosage of 50 mg every three weeks. It is aswell acclimated for some aplastic anemias.

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From:Natural herbal extracts

Wednesday, October 30, 2013

Some applications of Hygromycin B





Hygromycin B long-term feeding mouth can effectively control the pig tapeworm, esophagus nematodes and MAO nematode infection, this is because the product is not only effective for adult and larvae, but also can restrain the female worms lay eggs, so that the loss of insect body ability to reproduce. So. Pregnancy sow, hygromycin B is added to the full price feed, can protect the piglets in lactation period is not affected by ascaris infection. Hygromycin B is recommended for: prenatal 6 weeks and lactation sow; Less than 6 months of age piglets (most susceptible to worms).
Hygromycin B of chicken chicken roundworm, variations of renewal closed capillary nematode worm and birds all have good control effect.


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From:Lactic acid bacteria

Friday, October 25, 2013

Sodium Fusidate some effect




Sildenafil acid Sodium (Sodium Fusidate), white crystalline powder, solvent is a colorless and transparent liquid. Ingredient for the west to acid sodium, its chemical name is: alpha acetoxyl group of 16-3 beta, 11 beta 2 beta hydroxy - 4, 8 beta, alpha - trimethyl - 18 - to 14-5 beta, alpha cholesteric 10-17 (z) - 17 (20), 24 - diene - 21 - acid sodium,, west to sodium by inhibiting bacterial protein synthesis and produce sterilization effect, of a series of gram positive bacteria have strong antibacterial effect. Staphylococcus aureus, including to penicillin, methicillin and other antibiotic resistant strains, all our products are highly sensitive. , west acid sodium and clinical use of no cross resistance between other antimicrobial agents.

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From:Lactic acid bacteria

Wednesday, October 23, 2013

The role of Actidione





Actidione is a process of protein biosynthesis in eukaryotes have inhibition effect of the compound, it is gray Streptomyces (Streptomyces griseus) of a product. It by interfering with translocation steps in the process of protein synthesis and hinder the translation process. In the study of biological pharmacy cycloheximide is often used to inhibit protein synthesis of biological eukaryotic cells in vitro. This method is very effective, fast, and cheap. And by cycloheximide to remove from the test tube can quickly to cancel it.
Because cycloheximide has very strong toxicity, including damage to DNA, causing malformation fetus, and other effects of reproduction, including birth obstacles and toxicity of sperm), it is generally only used in vitro research applications, it is not suitable in the human body used as antimicrobial. In the past it was used as a fungicide in agriculture, but due to the increasing awareness of the dangers of it the usage has been rarely.
Alkali can destroy cycloheximide, so if the countertop or container is cycloheximide pollution as long as the use of harmless after alkali solution (such as soap) washing is ok.


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From:Lactic acid bacteria

Monday, October 21, 2013

Some of the role of Polyaluminium Chloride



Polyaluminium chloride is a kind of inorganic polymer flocculant, is referred to as "for poly aluminum, abbreviations for PAC, due to the effect of bridge of the hydroxyl ions and polyvalent anions polymerization production, charge higher molecular weight of inorganic polymer water treatment agent. On the form and can be divided into two kinds of solid and liquid, and solid according to different colors is divided into brown, yellow and white, different colors of polyaluminium chloride on the application and production technology is also a larger difference between the two.
role
Poly aluminum chloride (us) its flocculation performance is as follows:
A strong electric neutralization, colloidal substance in water.
B, the hydrolysate of suspended solids in water adsorption good bridging.
C, selective adsorption of soluble substances.
Polyaluminium chloride is a kind of inorganic polymer coagulant, due to the effect of bridge of the hydroxyl ions and polyvalent anions polymerization production, charge higher molecular weight of the characteristics of inorganic polymer water treatment agents, mainly determined by the working principle of pressure atomizer.


Friday, October 18, 2013

The basic information of the Sancycline





CAS no. : 808-26-4
English name: Sancycline
English synonyms: GS 2147; Bonomycin; NSC - 51812. Norcycline; SANCYCLINE; Sancycline Hydrochloride; 6 - Demethyl - - deoxytetracycline; (as 4 s, 4, 5 ar, 12 as) - 4 - (Dimethylamino) - 3, 11,10,12,12 a - tetrahydroxy - 1 -,4,4 dioxo - 1 a, 5, 5 a, 6 of the final three a - octahydro - 2 - naphthacenecarboxamide; (as 4 s, 4, 5 ar, 12 as) -,4,4 4 - (Dimethylamino) - 1 a, 5, 5 a, 6 of the final three a - 3,10,12,12 octahydro - a - tetrahydroxy - - 11 - dioxo 1-2 - naphthacenecarboxamide
Chinese name: mountain ring
English synonyms: mountain ring element; Ring element; Go armour ammonia tetracycline
CBNumber: CB0420370
Molecular formula: C21H22N2O7
Molecular weight: 414.41


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From:Lactic acid bacteria

Tuesday, October 15, 2013

What is G418 SulfateGeneticin?





G418 is an aminoglycoside antibiotic , the molecular genetic tests , is the most commonly used stably transfected resistance screening reagents. By inhibiting the transposon Tn601, Tn5 gene ribosome interference function block protein synthesis, such as prokaryotic and eukaryotic cells to produce toxins , including bacteria , yeast, plant and mammalian cells , including protozoa and worms. When the neo gene was integrated into the DNA of eukaryotic cells , the neo gene is able to start the coding sequence is transcribed into mRNA, which acquired resistance to aminoglycoside phosphotransferase product efficient expression , the cells which acquired resistance selection in G418 containing of the growth medium . This selection features G418 , has been in gene transfer , gene knockout , transgenic animals resistance screening and other aspects can be widely applied .
Shipped at room temperature , dry storage at room temperature , soluble in water , methanol , and the solution stored at -20 ℃ eukaryotic cell lines because each different sensitivity to G418 , or the lines of the new cell lines stably transfected with non- stable transfection Kill cells required amount will need to experiment optimized. Optimum dosage curve obtained through the establishment of cell death . The cells were diluted to 1000cell/ml, adding 100ul per well of 24-well plates with the medium , the G418 concentration in each well diluted to 0,100,200,300,400,500,600,700,800,900,1000,1100 ug / ml in 12 levels , cultured for 10-14 days in all cells death lowest concentration as a benchmark, usually around 400-800 , screening than this concentration no matter how high a level to maintain the use of filtering half the concentration can be.


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From:Lactic acid bacteria

Sunday, October 13, 2013

BOC-L-Asparagine nature of the introduction




Chinese Name : BOC-L- asparagine
Chinese Synonyms : N- t- butoxycarbonyl -L- asparagine ; BOC-L- asparagine ; N (α) - tert- butoxycarbonyl -L- asparagine ; protected amino acid ; BOC-L- asparagine amide ; BOC- asparagine ; N-(Α)-BOC-L- asparagine acid; tert-butoxycarbonyl group - asparagine
Product Name : BOC-L-Asparagine
English Synonyms : T-BUTYLOXYCARBONYL-L-ASPARAGINE; TBOC-L-ASPARAGINE; N-TERT-BUTOXYCARBONYL-L-ASPARAGINE; NT-BUTOXYCARBONYL-L-ASPARAGINE; NT-BOC-L-ASPARAGINE; N2-[(1,1 -Dimethylethoxy) carbonyl]-L-asparagine; NALPHA-BOC-L-ASPARAGINE; N-ALPHA-T-BOC-L-ASPARAGINE
CAS No. : 7536-55-2
Molecular formula : C9H16N2O5
Molecular Weight: 232.23
EINECS Number: 231-405-2
Related Categories : Amino Acid Derivatives; Amino Acids; amino acids ; Asparagine [Asn, N]; Boc-Amino Acids and Derivative; Amino Acids (N-Protected); Biochemistry; Boc-Amino Acids; Boc-Amino acid series; amino acids and their derivatives ; biochemical reagents ; biochemicals ; amino acids ; Heterocycles
Mol File : 7536-55-2.mol
Melting point 175 ° C (dec.) (lit.)
Refractive index -7 ° (C = 1, DMF)
Storage conditions -20 ° C
Chemical Properties white crystalline substance ; soluble in DMF, insoluble in petroleum ether ; decomposition point of 175-180 ℃; Specific rotation [α] 20D-9 ° (0.5-2 mg / ml, DMF).
Use for peptide synthesis , as protected amino acids monomers.
Production methods with tert -butoxycarbonyl chloride ( or azide ) and L- asparagine as a raw material, and then acidified with citric acid acylation , recrystallization products.


Friday, October 11, 2013

Sodium hypochlorite Introduction





Sodium hypochlorite, chemical formula NaClO, is sodium hypochlorite. Sodium hypochlorite, hypochlorous acid produced by the reaction with carbon dioxide is the active ingredient in bleach.
Indications: Root canal irrigation.
Drug Category: Dental treatment - other commonly used drugs [1]
Risk category: corrosive substances
Pathways: inhaled, ingested, percutaneous absorption
Health hazards: frequent hand contact with the product of the workers, palms sweating, nail thinning, hair loss. This product has sensitization. This product may cause the release of chlorine poisoning.
Environmental hazards: No significant pollution.
Explosion Hazards: This product is flammable, corrosive, can cause the body burns, with sensitivity.
Dosage: Rinse the root canal, with 1 ~ 2ml, 1% ~ 5.25% of the solution, rinse, while washing edges attract.


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From:Metal Cleaning Agent

Wednesday, October 9, 2013

Basic chromic sulfate use and preparation




Purpose:
Basic chromic sulfate is mainly used for tanning leather . Raw material for the production of chromium hydroxide . Industrial dye used in the production of reactive black dye . Printing and dyeing industry as a mordant .
Preparation :
Basic chromic sulfate production methods are mainly organic reduction and sulfur dioxide reduction . Sodium dichromate organic reduction mother liquor solution of sodium hydrogen sulfate (40 ~ 42 ° Bé) or sulfuric acid in a lead-lined or glass-lined reactor equipped with a stirrer with stirring , after acidification , the reducing agent is added slowly with stirring sucrose , the reduction of hexavalent chromium , the reaction solution was maintained at the end of boiling , is conducive to complete the reaction.
The reaction product is viscous syrupy solution, add water, the solution concentration was adjusted to 40 ~ 42 ° Bé, first by natural cooling , then the cooling crystallizer chilled to below 10 ℃ , so that part of sodium sulfate crystals to generate mirabilite , centrifugal separation , the system product liquid is obtained basic chromium sulfate , and then concentrated and dried to obtain a solid product of basic chromium sulfate . Its
8Na2Cr2O7 +48 NaHSO4 + C12H22Ol1 → 16Cr (OH) SO4 +32 Na2SO4 +43 H2O +12 CO2 ↑
8Na2Cr2O7 +24 H2SO4 + C12H22O11 → 16Cr (OH) SO4 +8 Na2SO4 +27 H2O +12 CO2 ↑


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From:pharmaceutical chemicals

Tuesday, October 8, 2013

Wire Netting types





Barbed wire (Wire Netting), mainly for the tardy action infantry and vehicles , sub- fixed and mobile -two. Barbed wire is fixed stakes and barbed wire , etc. to build from ; mobile barbed wire is mass-produced and shipped from the factory to the battlefield to temporarily set a diameter of 70-90 cm, length 10 meters , set the speed, anti- destruction of high strength, armored cars and other vehicles can be tardy action . Lift the barbed wire, people often think of the battlefield , prisons, border lines, and special scenes. Indeed, barbed wire , once invented , it was widely used in military and defense projects ; now in peacetime , the barbed wire is also widely used .

Barbed wire type
Barbed wire production process is divided into: braided , spot type Chela type , punching , wrap-around , screwed into sex , anchor type, etc. collectively referred to as wire or steel mesh .
Barbed wire further development and growth , with many of today's species such as : fence, fence, crimped wire mesh, wire mesh, welded wire mesh, welded mesh , welded wire mesh, crimped wire mesh , wire fence ; mesh , etc.
Barbed wire Related Products: flood control flood control with barbed wire : gabion , gabion mesh , plastering mesh, gabion , honeycomb grid , eco- grid, eco- cage , reinforced road networks, port engineering network, retaining walls, green grid , heavy hexagonal . Traffic safety with barbed wire : highway fence , highway fence, airport fence , rail fence, bridge fence , plant fence, stadium fence, workshop and warehouse fence, fence construction sites , residential fence . Farming planting with barbed wire : Dutch mesh, chain link fence, diamond mesh . Mine with barbed wire : underground metal mesh , coal graticule , coal use mesh, mine safety nets, Mine Support Network , Mine Safety Support Network , mine mesh, barbed wire mines , coal barbed wire, woven wire mesh coal , coal plain weave mesh .
Welded wire mesh , welded wire mesh is made ​​of high quality Q195 low carbon steel wire , welded row , then cold-plating ( electroplating ) , hot dipped , PVC plastic bag , such as surface passivation, plastics processing , flat surface , mesh mesh uniform, solid solder joint , local good machining performance , stability , corrosion resistance, corrosion resistance grid mesh products. In welded wire mesh galvanized after forming ( electroplating or hot dip ) ; product is made ​​of high quality galvanized iron wire through sophisticated automated machinery welded . Has a solid solder joint , reasonable structure , mesh uniform characteristics , flat surface , firm structure , strong integrity , strong corrosion resistance can also be used in the construction of floor heating special mesh . Now available at many domestic areas are widely used


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Thursday, August 29, 2013

Ethylene glycol diglycidyl ether of some of the information




Appearance: light yellow or colorless transparent liquid.
Solubility: soluble in ethanol, acetone and benzene and other organic solvents, slightly soluble in water.
Description: Ethylene glycol diglycidyl ether is a glycol ether chain containing an epoxy resin, an epoxy resin or a low viscosity water-soluble aliphatic epoxy resin, epoxy equivalent 112 ~ 135g/eq or an epoxy group content of 28.5% to 33. O%, viscosity of 10 ~ 100mPa · s, the chlorine content of 9.5%. Soluble rate of 95% to 100%.
Preparation: ethylene glycol and epichlorohydrin.
Usage: often mixed with bisphenol A type epoxy resin as a low viscosity compound, casting material, impregnating liquid, adhesive, resin modifier, fabric treatment agents. Are used as epoxy reactive diluents, stabilizers paraffin.


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From:chemical reagent

Thursday, August 22, 2013

2,5-Dithiobiurea description of each parameter




Preparation:
Method one: The preparation method is the reaction vessel with stirring hydrazine sulfate into wet basis, a small amount of catalyst is added, and then into ammonium thiocyanate, open jacket steam heating under reflux 3.5h, cooled, discharge, filtered, washed with water , vacuum filter to dryness to give the finished product.
Method Two: Hydrazine sulfate and thiocyanate amines by condensation, heavy discharge, too.
Storage features: Treasury ventilated low-temperature drying; oxidants, acids stored separately
Toxicity rating: high toxicity
Acute toxicity: Oral - Rat LD50: 500 mg / kg; celiac - Mouse LD50: 100 mg / kg
Health Hazard: heat decomposition of toxic emissions of nitrogen oxides and sulfur oxides
Category: Pesticides
Extinguishing Media: Water, dry chemical, dry sand, carbon dioxide, foam, extinguishing agent 1211
Use one: Is  2,5-Dithiobiurea  leaf blight fungicide intermediates.
Uses two: pesticide and pharmaceutical intermediates.
Appearance: Bisthiourea pure product as a white crystalline solid, mp206 ~ 208 ℃, in hot water with some solubility, soluble in pyridine, triethylamine, dimethylformamide and general solvent.



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From:chemical reagent

Tuesday, August 13, 2013

Aluminum tert-butylate basic information




Chinese Name: tert-butoxy aluminum
Chinese Synonyms: tert-butoxide
English name: aluminium tri-tert-butanolate
English Synonyms: Aluminum tert-butoxide; Aluminum tert-butanolate; Aluminum tert-butylate; Aluminum tri-tert-butoxide; Aluminum, tri-tert-butoxy-; Aluminum, tris-tert-butoxy-; NSC 4648; Tri-tert- butoxyaluminum; 2-Propanol, 2-methyl-, aluminum salt; 2-Propanol, 2-methyl-, aluminum salt (3:1); Aluminium tri-tert-butanolate; tert-Butyl alcohol, aluminum salt (8CI); Aluminum t-butoxide; aluminum tris (2-methylpropan-2-olate)
CAS :556-91-2
EINECS :209-146-1
Formula: C4H10AlO
Molecular Weight: 101.1015


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From:chemical reagent 

Monday, August 12, 2013

Butyl methanesulfonate some information




Chinese name: methyl sulfonate ester
Chinese Synonyms: methyl sulfonate ester; butyl mesylate
Product Name: N / A
English Synonyms: Butyl methanesulfonate
CAS No.: 1912-32-9
Formula: C5H12O2S
Mol File: Mol File
Description: This product is colorless transparant liquid.It is soluble in alcohol.It is toxic.It is used for organic synthesis.This product should be sealed.


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From:chemical reagent

Tuesday, August 6, 2013

N-Bromosuccinimide chemical reactions related




N-Bromosuccinimide reaction of olefins
NBS can olefin 1 in aqueous solution reaction of hydroxy alkyl bromide 2. The optimal reaction condition is at 0 ° C under an olefin dissolved in dimethyl sulfoxide, dimethoxyethane, tetrahydrofuran, tert-butanol, 50% aqueous solution of any one of the segments joined NBS. The reaction mechanism is: i) an onium bromide ion generation; ii) the nucleophilic attack of water molecules. Stereoselectivity for the trans-adduct in accordance with the law Markov.
The products of the reaction include the α-bromo ketone and two bromo compound. The new NBS purified by recrystallization can reduce the formation of these by-products. If no water was added, and the addition of other nucleophiles may bifunctional synthesis of other compounds.
Hofmann rearrangement reaction of bromide
N-bromosuccinimide in a strong base (e.g., 1,8 - diazabicyclo [5.4.0] undec-7 - ene (DBU)) state can be re-primary amide by Hofmann discharge reaction intermediate isocyanates. The isocyanate compound and a hydroxyl group (e.g., methanol) to form a readily hydrolyzable carbamate and separation.


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From:chemical reagent

Sunday, August 4, 2013

Some properties of 1,4-Butanesultoned




Chemical Properties: colorless liquid. Mp 12.5-14.5 ℃, boiling point 134-136 ℃ (0.53kPa), the relative density of 1.331 (20/4 ℃), refractive index 1.4640, with a variety of organic solvents, insoluble in water.
Uses: medicine, chemical reagents, surface active agents, dye-sensitized colored intermediates. Electroplating intermediates starting materials. Sulfonation agent for organic fine chemical intermediates for the pharmaceutical, photographic materials, lithium batteries, electronic plating, household chemicals, etc. used as photosensitive 67649
Production methods: by tetrahydrofuran and ethyl chloride chlorine butyl acetate, and then reacted with sodium sulfite hydroxybutyric acid, dehydration in the final product. About 40% overall yield.
Category: toxic substances
Toxicity rating: high toxicity
Acute toxicity: Oral - Rat LD50: 500 mg / kg; celiac - Mouse LD50: 138 mg / kg
Health Hazard: Thermal decomposition emits toxic fumes of sulfur oxides
Storage features: Treasury ventilated low-temperature drying; kept separate from raw materials and food
Extinguishing Media: Water, dry chemical, dry sand, carbon dioxide, foam, extinguishing agent 1211


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From:chemical reagent 

Thursday, August 1, 2013

Methyl caprylate some information about each parameter


Methyl caprylate is a colorless to pale yellow clear liquid. With wine, fruit, orange aroma. And difficult to dissolve in water, soluble in alcohol, ether, oils and other organic solvents. Naturally present in the iris and creamy strawberry, pineapple, plums and other essential oils. Preparation methods generally two types: one, from coconut oil fatty acids in the presence of an alcohol solution of hydrochloric acid gas derived. 2, by the bitterness esterification with methanol derived. Colorless, oily liquid. Mainly for the preparation of pineapple, berries and fruit flavor.


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From:Natural fatty acids

Tuesday, July 30, 2013

egetable ethyl oleate physicochemical properties




Physical and chemical properties: Vegetable ethyl oleate is a colorless or pale yellow oily liquid with slight odor and taste similar to olive oil, the relative density of 0.87 ~ O.874, the boiling point of 205 ~ 208 ℃. Similar properties and fatty oil, the advantage of low viscosity, at 5 ℃ can maintain clarity, but it will change after storage. With alcohol, ether, chloroform, fatty oils and liquid paraffin nettle mixed organic solvent, exposed in the air easily oxidized, preferably nitrogen Mesa storage is dark cool place.
Usage and dosage: ethyl oleate quickly absorbed by tissue, is an excellent solvent for injection. British Pharmacopoeia, testosterone propionate, ethyl oleate and other seven can be used as injection solvent.


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From:Natural fatty acids

Sunday, July 28, 2013

Coconut oil oleic acid talk about some of the uses



Coconut oil oleic acid, the state is white or creamy yellow solid, waxy or oily liquid. For textile auxiliaries, emulsifiers SBR, high-soap soap, synthetic intermediates of various surfactants. Coconut oil oleic acid acid is made ​​up of eight, ten acid, lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, etc., lauric acid, accounting for about 50%.

Coconut oil is extracted coconut harvest mature coconut trees (coconut) from the kernel or meat. Throughout the tropical world, it provides millions of people for generations the main source of fat in the diet. It has been widely used in food, medicine, and industry. What makes coconut oil different from most other dietary oils basic building blocks of oil or fatty acids. Glycerides of coconut oil, medium chain fatty acids (MCFA) based components. Most of the fat in the human diet long-chain fatty acids of long chain fatty acid glycerides. It is used in a raw material such as an engine, engine oil, transformer oil and herbicides etc.It is also used in the cosmetics industry, skin care and medicine.



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From:Natural fatty acids

Friday, July 26, 2013

Properties of Vetetable oleic acid



Nature:Vetetable oleic acid is a colorless oily liquid, with animal oil or vegetable oil smell, long in the air the color gradually deepened,industrial product is yellow to red oily liquid, with lard smell.
Pure oleic acid melting point 16.3 ℃, boiling point 350-360 ℃, the relative density of 0.8935 (20/4 ℃), refractive index 1.4585-1.4605, flash is 189 ℃.
Upstream raw materials: castor oil, soybean oil, sulfate,magnesium sulfate, sodium chloride, sorbitol, caustic soda, fatty acid, vegetable oil, palm oil.
Downstream products: two poly acid, cyanuric acid, acid,pentaerythritol oleic acid ester, three hydroxy methyl propanethree oleic acid ester, ethyl oleate, oleic acid lauryl alcohol ester,paint, alkyd ready-mixed paint, amino baking varnish, polyestervarnish, detergent, 808 high temperature leveling agent BOF,uniform dyeing agent GS, oleic acid polyoxyethylene esters.
Soluble in ethanol, ether, chloroform and other organic solvents,insoluble in water. Flammable. In case of alkali easysaponification, solidification after the formation of soft white solid.Easily in the heat oxidation, polymerization or decomposition. Non-toxic.
Vetetable oleic acid and the action of nitric acid, then isomerized to trans isomers of oleic acid, the melting point was 44 ~ 45 ℃;hydrogenation is a mixture of stearic acid; oxidation with potassium permanganate, pelargonic acid and azelaic acid. Oleic acid due to the presence of double bond, placed long-term in the air can occur from oxidation, partial into carbonyl compounds,have corrupt rancid odor, which is why oil deterioration.Commercial oleic acid, containing 7% ~ 12% saturated fatty acids,such as palmitic acid and stearic acid.
Vetetable oleic acid sodium or potassium salt is a component ofsoap. Pure sodium oleate ability, can be used as emulsifying agent, surface active agent, and can be used for the treatment ofcholelithiasis. Other metal salt Vetetable oleic acid can also beused to waterproof fabrics, lubricant, polishing agent and so on,the barium salt can be used as a rodenticide.



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From:Natural fatty acids

Thursday, July 25, 2013

C12 Alcohol brief description of the


Product name: C12 Alcohol
CAS :112-53-8
Fomular: C12H26O
Molecular weight: 186.33 g / mol
Description: This artefact is a white solid or achromatic aqueous with the melting point 22-27 º C and the baking point 258-265 º C.It is baffling in baptize or glycerin.Soluble in Propanediol, ethanol, ethyl ether, chloroform and benzene.It has a that appears to smell of flower.It is burnable, acid and adverse to environment.It is acclimated in the alertness for the apparent alive abettor in fat booze ethers sodium, K12 and AEO.Used in the processing aid in the accomplish of able bactericide and textile, leather



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From:Natural fatty acids

Tuesday, July 23, 2013

1 - (4-methylphenyl)-Ethanone uses and properties of



1 - (4-methylphenyl)-Ethanone as colorless needle-like crystals or nearly colorless liquid at lower temperatures that line solidified, was strong and hawthorn fruit and floral aromas like, similar acetophenone aroma. Melting point 28 ℃. Boiling point 225 ℃ (98.1kPa), 112.5 ℃ (1.47kPa), the relative density of 1.0051 (20/4 ℃), refractive index 1.5335, flash point 92 ℃. Soluble in ethanol; ether; benzene; chloroform and propylene glycol, almost insoluble in water. Soluble in ethanol and most of the non-volatile oil, slightly soluble in propylene glycol and mineral oil, insoluble in glycerin and water. Natural products found in rosewood essential oil, oil of mimosa flowers.
Production method
From toluene and acetic anhydride in the presence of anhydrous aluminum chloride, the acetylation reaction. The dried toluene and powdered anhydrous aluminum chloride added to the reaction pot, acetic anhydride was added dropwise with stirring, the temperature was gradually raised to 90 ℃, reaction to release a large number of hydrogen chloride gas. No reaction to produce hydrogen chloride gas, cooled to room temperature, poured into a mixture of ice and concentrated hydrochloric acid and stirred until all dissolved aluminum. The toluene layer was separated, washed with water, washed with 10% sodium hydroxide solution to alkaline, and then washed. Dried over anhydrous magnesium sulfate, vacuum distillation, collecting 93-94 ℃ (0.93kPa) distillate, methyl acetophenone, yield 86%. The improved method is to equimolar amounts of aluminum trichloride and acetyl chloride (or acetic anhydride) was allowed to stand under heating to make the binding thereto Carbon disulfide was added dropwise a toluene insoluble. Calculated by acetyl chloride, the weight yield of 110%.

Instructions for use:
1 - (4-methylphenyl)-Ethanone hawthorn has a similar sub-floral fragrance, and like alfalfa; honey; strawberry flavor, sharp and sweet floral scent. Can be used for the preparation of lilac soap acacia type flavor, etc., can make fruit food flavor. Can be used to shy flower, hawthorn flowers, acacia, locust, primrose, sunflower, hyacinth, lilac, lily, wood, moss, incense and other types. With coumarin, anise aldehyde, piperonal were used in soap lavender, incense Wei, chypre, a new type of mowing. Can be used to trace almonds, vanilla bean flavor of food flavor, but also a small amount for tobacco flavor.



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