Enalapril for white or white crystalline powder, odourless, tasteless. Easily dissolved in methanol, slightly soluble in water, slightly soluble in acetone. The melting point of 142-142 ℃ (decomposition). For angiotensin converting enzyme inhibitor, absorbed in the liver to ester hydrolysis is enalaprilat, and play the role of inhibition of angiotensin converting enzyme. Suitable for all kinds of degree of hypertension, renovascular hypertension, and diabetes treatment for hypertension patients; Can also be used for the treatment of chronic congestive heart failure, especially in the conventional application of digitalis or diuretic is difficult to control, can delay the progress of clinical symptoms of congestive heart failure and minimize the need for hospitalization. This product effect is better than that of the captopril, adverse reactions and lighter, so it is increasingly widely used, in the treatment of high blood pressure drug of choice. With other anti-hypertensive drugs, especially the diuretic step-down, enhanced by use of this product should be discontinued before the diuretic or start from small doses. This product can make the potassium rises, unfavorable and potassium diuretic or potassium supplement share.
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