Pemetrexed is pyrrolopyrimidine-based, multi-targeted antifolate with ample in vivo anti-tumor activity.Pemetrexed is chemically agnate to folic acid and is in the chic of chemotherapy drugs alleged folate antimetabolites.
Its antiproliferative activity has been approved in a array of solid tumors including non-small corpuscle lung, breast, mesothelioma, colorectal, pancreas, stomach, bladder, cervical and arch and neck.
It works by in purine and pyrimidine amalgam thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (REGISTRY) acclimated to arrest three enzymes.
more about: Pemetrexed disodium hepthydrate
from: Pharmaceutical Ingredients
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