Actidione is a process of protein biosynthesis in eukaryotes have inhibition effect of the compound, it is gray Streptomyces (Streptomyces griseus) of a product. It by interfering with translocation steps in the process of protein synthesis and hinder the translation process. In the study of biological pharmacy cycloheximide is often used to inhibit protein synthesis of biological eukaryotic cells in vitro. This method is very effective, fast, and cheap. And by cycloheximide to remove from the test tube can quickly to cancel it.
Because cycloheximide has very strong toxicity, including damage to DNA, causing malformation fetus, and other effects of reproduction, including birth obstacles and toxicity of sperm), it is generally only used in vitro research applications, it is not suitable in the human body used as antimicrobial. In the past it was used as a fungicide in agriculture, but due to the increasing awareness of the dangers of it the usage has been rarely.
Alkali can destroy cycloheximide, so if the countertop or container is cycloheximide pollution as long as the use of harmless after alkali solution (such as soap) washing is ok.
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From:Lactic acid bacteria
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