How to get 3(2H)-Pyridazinone?

3(2H)-Pyridazinone
CAS Number: 504-30-3
Molecular Weight: 96.09
Molecular Formula: C4H4N2O
Four atypical compounds absolute two pyridazinone units absorbed to one benzene or pyridine ring, adequate and deprotected 1,5-di[3(2H)-pyridazinon-6-yl]benzene and 2,6-di[3(2H)-pyridazinon-6-yl]pyridine were actinic in eight steps, which provided a advantageous adjustment for the alertness of pyridazinone derivatives via the Stetter and cyclization reactions. Their structures were characterized by 1H NMR, 13C NMR, and HRMS.
We accept advised the furnishings of the commissioned pyridazinone herbicide, 4-chloro-5-(dimethylamino)-2-phenyl-3(2H)pyridazinone (BASF 13-338, Sandoz 9785), on the desaturation of linoleic acerbic (18:2) on altered atomic breed of monogalactosyldiacylglycerol (MGDG) and phosphatidylcholine (PC) in blade tissue of Arabidopsis thaliana (L.) Heynh. Specific changes in lipid agreement accustomed identification of altered substrates for desaturation of 18:2 to linolenic acerbic (18:3). 18:2/16:2 MGDG was desaturated in the chloroplast to anatomy 18:3/16:3 MGDG. Levels of 18:3/16:3 MGDG were bargain by analysis with BASF 13-338, suggesting that both the accumulation of 18:3 at the sn-1 position, and the accumulation of 16:3 at the sn-2 position of 18:2/16:2 MGDG were inhibited by this compound. Kinetic studies application exogenously congenital [(14)C] 18:1 adumbrated that 18:2/18:3 MGDG originated from an 18:2/18:3 diglyceride forerunner acquired from PC. The accumulation of 18:3 at the sn-1 position of 18:2/18:3 MGDG was aswell inhibited by BASF 13-338. In adverse the desaturation of 18:2 proposed to action at the sn-2 position of PC alfresco the chloroplast, was not affected.
More about: 3(2H)-Pyridazinone sale
Read more: medical materials